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Lupus Science & Medicine® is a global, peer reviewed, open access online journal that provides a central point for publication of basic, clinical, translational, and epidemiological studies of all …
Clinical trial outcomes for SLE: what we have and what we need
The paradigm of drug approval in SLE currently relies on successful large phase III randomised controlled trials and a set of primary, secondary and additional end points. Taken together, …
05 Lifestyle for lupus patients: exercise, diet, and well-being ...
As systemic lupus erythematosus (SLE) is a chronic condition with a significant impact on physical and mental health, all potential interventions to improve quality of life are relevant for SLE …
Central nervous system infections in patients with systemic lupus ...
We aimed to conduct a systematic review and meta-analysis of studies on central nervous system (CNS) infections in patients with SLE, in order to describe their clinical and microbiological …
Alopecias in lupus erythematosus | Lupus Science & Medicine
Several patterns of hair loss can occur in lupus erythematosus (LE). Alopecias which show histological characteristics of LE are LE-specific, and include discoid LE (DLE), diffuse or …
SARS-CoV-2 spike aggravates lupus nephritis and lung fibrosis in ...
Objective COVID-19 induces the development of autoimmune diseases, including SLE, which are characterised by inflammation, autoantibodies and thrombosis. However, the effects of COVID …
Cutaneous vasculitis in SLE | Lupus Science & Medicine
Cutaneous vasculitis was observed in 17.3% of patients with SLE. The mean time to cutaneous vasculitis after SLE diagnosis was 4.78 years (95% CI 3.96 to 5.60). Among patients who …
PO.5 E- poster session 5: lupus nephritis - Lupus Science & Medicine
Purpose The effect of belimumab (BEL) on renal outcomes has been previously demonstrated in the BLISS-LN study in patients with active lupus nephritis (LN).1 Here we evaluate the effect …
Utility of skin biopsy in patients with systemic lupus erythematosus ...
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that can affect multiple organs, commonly the skin in 70%–85% of patients.1 Cutaneous lupus is associated with the …
Major infections in newly diagnosed systemic lupus …
Objective To evaluate the risk of major infections and the relationship between major infections and mortality in patients with newly diagnosed SLE. Methods A newly diagnosed (<3 months) …