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LOUISVILLE, Ky. - After capturing a road win over Virginia for the first time in almost 35 years, the Louisville men's basketball program has another tough task right in front of them, returning home to host Clemson.

Take a look at how the Cardinals stack up against the Tigers for their Tuesday matchup, and who the statistical models favor:

The Tigers and Cardinals have quietly become one of the conference’s best rivalries since Louisville joined the ACC, playing several highly contested football and baseball games

The Clemson Tigers (12-3, 4-0 ACC) hit the road to take on the Louisville Cardinals (10-5, 3-1 ACC) Tuesday night. It’s time to continue our College Basketball odds series with a Clemson-Louisville prediction and pick.

Louisville seeks a fifth straight win on Tuesday when the host Cardinals entertain Clemson, which is also enjoying a strong start to Atlantic Coast Conference play.