Unexpected mutations in blood stem cells may help protect against Alzheimer’s disease. A new study published in the journal ...

Researchers say the hormone dopamine may be used as a treatment for Alzheimer's disease as it stimulates the production of an enzyme known to break down beta-amyloid via a mouse model.

Northwestern Medicine scientists have discovered that mitochondria are not necessary for the proliferation of specialized immune cells in the central nervous system, but do help those cells respond to ...

After using mouse models of AD, researchers discovered that amyloid beta produced by oligodendrocytes was associated with the formation of plaques. The team found that by blocking the production of ...

Learn about the role of beta-amyloid in Alzheimer's disease, current detection methods, and whether diet and exercise affect beta-amyloid levels.

Although the exact mechanism for LPS to induce Alzheimer’s pathogenesis is not fully elucidated, various research studies described that LPS-induced neuroinflammation impairs memory function via ...

Researchers have found a different and promising way to remove the noxious amyloid plaques in Alzheimer's disease: by directly mobilizing immune cells to consume them.

Researchers at Weill Cornell Medicine have demonstrated how amyloid beta, a peptide associated with Alzheimer's disease, can interact with a protein receptor on immune cells in the brain. This ...

Here, we report that nasally administered anti-CD3 monoclonal antibody in the 3xTg AD mouse model reduced microglial activation and improved cognition independent of amyloid beta deposition.

To uncover this, the scientists ran five mouse models with Alzheimer’s and examined the relationship between issues in the lyosome-authophagous pathway and the identification of amyloid beta.

The team also showed, administering the beta secretase inhibitor LY2886721 that reduces amyloid beta levels, decreased the size of brain melanoma metastases by about half in mouse models.