The mice used in this study lacked amyloid plaques on blood vessels, so the researchers could not evaluate what happens when blood vessel plaques are removed. They are working with a different mouse ...

Alzheimer's disease progression linked to microglia fat metabolism, potential new treatment target identified in recent study ...

Clumps or plaques of the protein beta-amyloid in the brain are a hallmark of a type of dementia called Alzheimer’s disease. When beta-amyloid plaques form, they disrupt communication between ...

Mice that overexpress the human mutant amyloid precursor protein (hAPP) show learning deficits, but the apparent lack of a relationship between these deficits and the progressive β-amyloid plaque ...

The triggering receptor expressed on myeloid cells 2 (TREM2) plays a pivotal role in the activation of myeloid cells and is currently being investigated as a potential therapeutic target in several ...

Whole blood exchange reduces the formation of amyloid beta plaques in mouse models of Alzheimer's disease. The corresponding study was published in Nature. A buildup of amyloid proteins in the brain ...

The researchers discovered that STING, an immune molecule meant to protect the brain, may actually be making things worse as ...

New research shows that low-intensity repetitive transcranial magnetic stimulation (rTMS) can restore key synaptic structures ...

Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to them, forming a sort of external stomach and releasing ...

"Protein tangles and plaques have been the focus of Alzheimer's treatments for decades," says Walton. "What we're showing for the first time is that immune cells can be trained to recognize not just ...

Alzheimer’s disease starts with a sticky protein called amyloid beta that builds up into plaques in the brain, setting off a chain of events that results in brain atrophy and cognitive decline. The ...