San Francisco 49ers cornerback Deommodore Lenoir has agreed to a five-year, $92 million extension to stay with the team ...

The Front Street entertainment zone was made possible by state Sen. Scott Wiener’s Senate Bill 76, a law passed last year ...

A "remarkable" new sea slug nicknamed the “mystery mollusk” has been discovered swimming deep in the ocean's "midnight" zone.

Shai Gilgeous-Alexander scored a career-high 45 points, and the Oklahoma City Thunder beat the Los Angeles Clippers 134-128 on Monday night in their first game this ...

Get ready for a new-look San Francisco Board of Supervisors next year. Though there are still a few thousand votes to count, ...

But planetarium-goers in San Francisco can see an opera, “Everest: Opera in the Planetarium,” as San Francisco’s Opera ...

With voters’ rejection of Proposition 6, involuntary servitude remains in the state constitution. And as CalMatters local ...

In the world of cell therapy, Silicon Valley has long recognized that technological innovation is the key to solving ...

A young girl diagnosed with a rare genetic condition which means she will lose her eyesight has begun a 'visual wish list' ...

Ryan Kalkbrenner and No. 14 Creighton will look to continue their sizzling start to the season on Wednesday night when ...

The Kansas City Chiefs designated running back Isiah Pacheco and defensive end Charles Omenihu to return to practice this ...

A new blood vessel-like coating could make medical devices including catheters and stents safer for millions of patients, ...