The Tigers won a pitching duel between Tarik Skubal and Hunter Brown on a bases-loaded walk in the 10th inning on Tuesday.

DETROIT -- The Detroit Tigers will go for a three-game sweep on Wednesday afternoon. The Tigers (75-53) play the Houston Astros (69-57) at 1:10 p.m. at Comerica Park. Infielders Colt Keith, Zach McKinstry and Trey Sweeney; and outfielder Kerry Carpenter will be available off the bench. The full lineup is below.

Houston Astros outfielder Taylor Trammell left Wednesday's game against the Detroit Tigers on a cart after crashing into the center field fence in the first inning.

Detroit is in a good spot for a first-round bye, but there are still too many teams within shouting distance to fully relax. In the National League, the Brewers are a full five games ahead of the Tigers, while the Phillies, Cubs, and Dodgers are all within two games of Detroit.

The Houston Astros have been shut out in back-to-back games, but they remain 1.5 games up on the Seattle Mariners in the AL West heading into their series final

After failing to get much going in regulation, the Tigers walked off the Astros with a little help from pitcher Kaleb Ort.

For the first time since the 1985 season, the Astros have been shut out in three consecutive games after losing in 10 innings Tuesday.

BOTTOM LINE: The Houston Astros, on a three-game losing streak, take on the Detroit Tigers. Detroit has gone 41-24 in home games and 75-53 overall. The Tigers have gone 43-13 in games when they did not allow a home run.