Not only was there survivor carnage, but Fantasy Football waiver wires were active after last weekend’s games. Deebo Samuel, Cooper Kupp and Isiah Pacheco were just a few of the high-profile players ...

San Francisco 49ers quarterback Brock Purdy spoke about orchestrating the team's offense without playmakers Christian McCaffrey and Deebo Samuel.

Purdy still hasn't entirely shaken the "system" quarterback label and other denigrations. A chance for his rebuttal is now ...

Greg Scholz runs through the biggest fantasy football injury worries of Week 3, leading off with A.J. Brown's precarious ...

Injuries already are accruing across the NFL, knocking several star players out and forcing teams to turn to backups and ...

Aiyuk missed most of training camp due to a hold out, so a slow start isn't a huge surprise. Now, in Week 3, he should be up to speed and he gets a defense that has been pretty awful so far. The Rams ...

The San Francisco 49ers and Los Angeles Rams have aspirations of winning the NFC West and making another Super Bowl run, but ...

The 49ers are without Christian McCaffrey, Deebo Samuel and maybe George Kittle, while the Rams won’t have top receivers ...

On offense, Jordan Mason is coming off back-to-back 100-yard rushing games. Brock Purdy reached 300-yards passing and Deebo ...

The San Francisco 49ers could be without another key offensive player this week after All-Pro tight end George Kittle missed ...

Injuries stacked up quickly for the San Francisco 49ers leading up to their Week 3 showdown with the Los Angeles Rams.