Silent synapses are dormant neural connections that hold untapped brain potential. Discover how ketamine, exercise, and other ...

Discover recent clinical trial failures in depression and explore potential pathways for advancing antidepressant drug ...

Q4 2024 Earnings Call Transcript March 17, 2025 Operator: Good morning, ladies and gentlemen, and welcome to the NRx ...

Spravato is the first ketamine-based medicine approved to treat depression, and also the first of a new class of glutamate NMDA receptor-targeting drugs that have ended a decades-long drought at ...

The inhaled anesthetics affect many receptors (e.g., GABA A, glycine, acetylcholine, serotonin, NMDA) in manners that plausibly could explain anesthesia. Which receptors mediate anesthesia remains ...

Agents that affect the CNS, including antidepressants and antipsychotics, are often prescribed for patients undergoing surgical procedures. The results of a recent survey conducted at a large ...