Susan Collins (Maine) and Lisa Murkowski (Alaska) expressed reservations about the HHS nominee’s record on vaccines.

Maine's Republican senator plans to question both during separate hearings scheduled for Thursday morning, and she is seen as a possible swing vote.

Murkowski is a moderate with a history of bucking her party and Trump when she has felt it was the right thing to do.

President Trump on Friday said he wasn’t expecting Republican Sens. Lisa Murkowski (Alaska) and Susan Collins (Maine) to vote against his controversial nominee for secretary of Defense: Army veteran and former Fox News host Pete Hegseth.

Even as handicappers adjudged Pete Hegseth ’s confirmation as secretary of Defense to be all but certain, not one but two Republican senators indicated a hard pass on the poorly qualified bad boy from Fox News.

Republican Sen. Susan Collins voted Thursday against advancing President Donald Trump's choice for defense secretary, who has faced allegations of heavy drinking, financial mismanagement and abusive behavior toward women.

Two Republicans, Sen. Lisa Murkowski of Alaska and Sen. Susan Collins of Maine, broke ranks with Trump and his allies who have mounted an extensive public campaign to push Hegseth toward confirmation.

A defining duo of the first Donald Trump administration is back.

The Alaska Republican plans to vote against the confirmation of Pete Hegseth to lead the Department of Defense.

The US Senate on Friday approved Pete Hegseth as President Donald Trump’s defense secretary by a razor-thin margin, in which, Vice President JD Vance had to cast the tie-breaking vote.

Sen. Lisa Murkowski is opposing the nomination of Pete Hegseth to be President Donald Trump's Defense secretary.

President Donald Trump has nominated Kennedy to be the secretary of the U.S. Department of Health and Human Services, which oversees the U.S. Food and Drug Administration, Medicare and Medicaid and helps enforce the Affordable Care Act commercial health insurance rules.