Background Early-life inflammation has long been recognised as a key pathophysiological process in the evolution of cystic ...

Background Vitamin A, an essential micronutrient obtained through the diet, plays a crucial role in lung development and contributes to lung regeneration. We aimed to investigate its effect on adult ...

An 81-year-old woman presented to rheumatology with a relapse of her longstanding seropositive erosive rheumatoid arthritis (RA). Her medical history was significant for chronic lymphocytic leukaemia ...

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Objective Reduced functional capacity and muscle weakness are two major contributors to functional impairment in chronic obstructive pulmonary disease (COPD). The underlying causes of functional ...

Rationale Pulmonary rehabilitation is an effective treatment for people with chronic respiratory disease but is delivered to <5% of eligible individuals. This study investigated whether home-based ...

Background Severe obesity causes respiratory morbidity and mortality. The impact of obesity on the mechanics of breathing is not fully understood. Conclusions Obese subjects have markedly increased ...

Associations of pulmonary microvascular blood volume with per cent emphysema and CT emphysema subtypes in the community: the MESA Lung study ...

Correspondence to Dr Jamilah Meghji, Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK; jamilah.meghji{at}lstmed.ac.uk Background Post-tuberculosis lung ...

Background Previous studies have reported an association between weight increase and excess lung function decline in young adults followed for short periods. We aimed to estimate lung function ...

There remain many treatment uncertainties in cystic fibrosis (CF). With limited resources, research should focus on questions which are most important to the CF community. We conducted a James Lind ...

5 Department of Medicine, Faculty of Medicine, University of Valencia, Valencia, Spain 6 Department of Pharmacology, Faculty of Medicine, University of Valencia, Valencia, Spain Correspondence to Dr ...