Radioimmunotherapy using 225Ac, a highly cytotoxic α-particle emitter, has potential for treating advanced breast cancer, especially human epidermal growth factor receptor 2 (HER2)–positive cases. We ...

Dr. Bernd Pichler is a distinguished pioneer in preclinical and translational imaging, renowned for his groundbreaking work in multimodal imaging and imaging tracer development. As chair of the ...

Partial-volume effects (PVEs) arise from the limited spatial resolution of PET and SPECT imaging systems, causing the systematic underestimation of activity concentration in structures that may hold ...

RECIST was developed in 2000 by the National Cancer Institute, European Organization for Research and Treatment of Cancer, and National Cancer Institute of Canada, with revision to RECIST 1.1 in 2009 ...

Large language models have become enormously powerful tools for summarizing existing knowledge and generating text, figures, and references for scientific publications. This power can be abused to ...

Cytokines are small proteins that directly regulate immune cell proliferation and signaling. An improved understanding of cytokine expression in specific microenvironments provides critical insights ...

Semiconductor quantum dots (QDs), after surface modification to provide water solubility and biocompatibility, have a promising future in biomedical applications. In this study, a dual ...

The Nuclear Medicine Global Initiative was formed in 2012 by 13 international organizations to promote human health by advancing the field of nuclear medicine and molecular imaging by supporting the ...

The recent development of quinoline-based PET tracers that act as fibroblast-activation-protein inhibitors (FAPIs) demonstrated promising preclinical and clinical results. FAP is overexpressed by ...

The impact of PET image acquisition and reconstruction parameters on SUV measurements or radiomic feature values is widely documented. This scanner effect is detrimental to the design and validation ...

The aim of this work was to develop a theranostic method that allows prediction of prostate-specific membrane antigen (PSMA)–positive tumor volume after radioligand therapy (RLT) based on a ...

Targeted diagnosis and therapy enable precise tumor detection and treatment. Successful examples for precise tumor targeting are diagnostic and therapeutic radioligands. However, patients with tumors ...