In a recent essay, scientists challenge the prevailing genetic-focused model of cancer, advocating for a shift towards more ...

It's time for researchers to reconsider the current paradigm of cancer as a genetic disease, argued Sui Huang from the Institute for Systems Biology, USA, and colleagues in a new essay published March ...

For example, somatic mutations that affect cell division (particularly those that allow cells to divide uncontrollably) are the basis for many forms of cancer ... HAD ONE RED EYE AND ONE BLU ...

The right side of his face became so bloated that he could not open his eye. He developed a full ... to a particular gene and to a particular somatic mutation—a genetic change that had not ...

This review aims to synthesize the existing information on somatic oncogenic variants in patients' tumors from LAC. We included the frequency of somatic oncogenic variants of the most frequent tumors ...

Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its ...

UK-based clinical testing programme for somatic and germline BRCA1/2, ATM and CDK12 mutations in prostate cancer: first results. BMJ Oncology . DOI: 10.1136/bmjonc-2024-000592 ...

Tumor suppressor genes act as “brakes” to stop cells before they can travel down the road to cancer ... could be caused by either somatic or germ-line mutations. Knudson's combined data ...