We get back to full swing for Week 1 with all 16 SEC teams in action without there being a single SEC-SEC matchup. Unfortunately, 3 games (Alabama A&M at Arkansas, Illinois State at Oklahoma, and Long Island at Florida) did not have spreads posted by the time I sent the list out on Monday morning.

The Inside the Lines team uses its proven NFL model to identify our best sportsline player projections vs the best available odds to build our best bets.

BookmakersReview.com is kicking off the NFL season with its annual FREE NFL Pick’Em Pool, giving football fans the chance to compete for a share of $2,500 in Sportsbook Cash.

Joey Pollizze analyzes all 2025 fantasy football Week 1 defenses (DEF) -- streamers, sits/starts, and D/ST waiver wire pickups to add. His Week 1 rankings and tiers for all of the NFL defenses.

Given that every team is available and there are some big favorites on the board, Week 1 may seem like a free ticket in NFL survivor picks. Well, not so fast. Last year, the Cincinnati Bengals were 8-point favorites in the season opener against the visiting New England Patriots.