Half of the patients required a warfarin dose reduction and/or withheld dose, which further confirms the clinical relevance of this interaction. This INR increase was observed, on average ...
Specifically, we sought to determine (1) whether the within-patient mean warfarin dosage required to maintain INR values within the goal range of 2.0–3.0 was significantly different before and ...
warfarin dose and vitamin K intake) and genetic factors (CYP2C9 and VKORC1 genotype). In addition, patients with severe CKD had much poorer anticoagulation control (that is, spent less time in the ...