Feb. 11, 2025 — A new study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington ...

However, compared to the control group, subtle changes were detected in brain scans and spinal fluid biomarkers of those with Huntington's disease gene expansion. This indicates that the ...

Caption Shown are MRI scans of a Huntington’s disease (HD) sufferer’s brain (left) and a normal brain (right). In the HD brain, many brain cells have died and fluid (black areas) has filled in ...

HDBuzz reported live updates on Bluesky from the 2025 HD Therapeutics Conference. Read on for coverage of Day 3. #CHDI2025 ...

This microscope photo provided by the McLean Hospital's Harvard Brain Tissue Resource Center in January 2024 shows cells in the caudate nucleus structure of the brain in a person with Huntington's ...

developed a method to measure both CAG-repeat lengths and gene expression in individual brain cells of six deceased people with Huntington’s disease. The researchers analysed tissue from a brain ...

Federally funded research at Johns Hopkins offers new avenues for detecting brain disease long before it strikes ...

The stem cells were developed into neurons from the striatum, the brain region primarily impacted by Huntington's disease, making the model relevant to disease conditions. These neurons were then ...

Huntington's disease (HD) is a hereditary neurodegenerative disorder ... supported by the findings of atrophy (shrinkage) of the caudate nucleus on brain imaging. Today, DNA testing can reliably ...