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Immunotherapy Clears Amyloid Plaques in Alzheimer’s Mouse Model Researchers have found a different and promising way to remove the noxious amyloid plaques in Alzheimer's.
Researchers say the hormone dopamine may be used as a treatment for Alzheimer's disease as it stimulates the production of an enzyme known to break down beta-amyloid via a mouse model.
How exactly do amyloid plaques affect surrounding brain tissue, and does this change over time? Scientists led by Jörg Hanrieder at the University of Gothenburg, Sweden, tackled this question by using ...
Mice that overexpress the human mutant amyloid precursor protein (hAPP) show learning deficits, but the apparent lack of a relationship between these deficits and the progressive β-amyloid plaque ...
Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to them, forming a sort of external stomach and ...
Whole blood exchange reduces the formation of amyloid beta plaques in mouse models of Alzheimer's disease. The corresponding study was published in Nature. A buildup of amyloid proteins in the brain ...
Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to them, forming a sort of external stomach and releasing ...
The researchers discovered that STING, an immune molecule meant to protect the brain, may actually be making things worse as ...
The triggering receptor expressed on myeloid cells 2 (TREM2) plays a pivotal role in the activation of myeloid cells and is currently being investigated as a potential therapeutic target in several ...
Why Alzheimer’s scientists are rethinking the amyloid hypothesis Recent studies implicate the immune system and a herpes virus as potential contributors to development of disease ...
"Protein tangles and plaques have been the focus of Alzheimer's treatments for decades," says Walton. "What we're showing for the first time is that immune cells can be trained to recognize not just ...